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TORRES BENITO , Laura

Last name: TORRES BENITO

First name: Laura

May 9, 2016 (v1)

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Función de la proteína de supervivencia de motoneuronas (SMN) en la maduración funcional y organización sináptica en un modelo murino de atrofia muscular espinal

Torres Benito, Laura

La Atrofia Muscular Espinal (AME) es una enfermedad autosómica recesiva caracterizada por debilidad muscular y deterioro de la transmisión sináptica y pérdida de motoneuronas inferiores. La proteína SMN (Survival Motor Neuron) está codificada por dos genes: SMN1, que produce la proteína completa (SMN-FL), y SMN2, que mayoritariamente produce...

Uploaded on: March 25, 2023
April 20, 2021 (v1)

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SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals

Torres Benito, Laura Feodora Neher, Margret Cano, Raquel

Low levels of the Survival Motor Neuron (SMN) protein produce Spinal Muscular Atrophy (SMA), a severe monogenetic disease in infants characterized by muscle weakness and impaired synaptic transmission. We report here severe structural and functional alterations in the organization of the organelles and the cytoskeleton of motor nerve terminals...

Uploaded on: December 4, 2022
February 27, 2015 (v1)

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Notch Signaling Pathway Is Activated in Motoneurons of Spinal Muscular Atrophy

Lladó, Jerònia Caraballo Miralles, Víctor Tabares Domínguez, Lucía

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Uploaded on: March 27, 2023