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March 2020 (v1)Journal articleUploaded on: December 4, 2022
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July 2022 (v1)Journal article
International audience
Uploaded on: December 3, 2022 -
May 14, 2020 (v1)Journal article
EHD2 is a mechanotransducing ATPase localized in caveolae invaginations at the plasma membrane. EHD2 has recently been associated with several human cancers, however the significance of EHD2 transcript levels in cancer prognosis remains debated. Breast cancer is the most commonly occurring cancer in women and prognosis is variable depending on...
Uploaded on: December 4, 2022 -
2011 (v1)Journal article
Rho GTPases, which are master regulators of both the actin cytoskeleton and membrane trafficking, are often hijacked by pathogens to enable their invasion of host cells. Here we report that the cytotoxic necrotizing factor-1 (CNF1) toxin of uropathogenic Escherichia coli (UPEC) promotes Rac1-dependent entry of bacteria into host cells. Our...
Uploaded on: December 4, 2022 -
August 14, 2020 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
March 4, 2019 (v1)Journal article
Ubiquitin domain-containing protein 1 (UBTD1) is highly evolutionary conserved and has been described to interact with E2 enzymes of the ubiquitin-proteasome system. However, its biological role and the functional significance of this interaction remain largely unknown. Here, we demonstrate that depletion of UBTD1 drastically affects the...
Uploaded on: December 4, 2022 -
April 22, 2021 (v1)Journal article
To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways. By combining lipidomic and proteomic approaches with functional analysis, we have shown that ubiquitin domain-containing protein 1 (UBTD1) plays a crucial role...
Uploaded on: December 4, 2022 -
April 22, 2021 (v1)Journal article
To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways. By combining lipidomic and proteomic approaches with functional analysis, we have shown that ubiquitin domain-containing protein 1 (UBTD1) plays a crucial role...
Uploaded on: December 4, 2022 -
April 22, 2021 (v1)Journal article
To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways. By combining lipidomic and proteomic approaches with functional analysis, we have shown that ubiquitin domain-containing protein 1 (UBTD1) plays a crucial role...
Uploaded on: February 22, 2023 -
July 1, 2019 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
May 7, 2019 (v1)Journal article
Although tumorigenesis is dependent on the reprogramming of cellular metabolism, the metabolic pathways engaged in the formation of metastases remain largely unknown. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1a) plays a pleiotropic role in the control of cancer cell metabolism and...
Uploaded on: February 22, 2023 -
May 7, 2019 (v1)Journal article
Although tumorigenesis is dependent on the reprogramming of cellular metabolism, the metabolic pathways engaged in the formation of metastases remain largely unknown. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1a) plays a pleiotropic role in the control of cancer cell metabolism and...
Uploaded on: December 4, 2022 -
July 1, 2019 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
July 1, 2019 (v1)Journal article
International audience
Uploaded on: February 22, 2023