T

TUCCINARDI T.

Last name: TUCCINARDI T.

2021 (v1)

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New therapeutic strategy for overcoming multidrug resistance in cancer cells with pyrazolo[3,4‐d]pyrimidine tyrosine kinase inhibitors

Podolski-renic A. Dinic J. Stankovic T.

Tyrosine kinase inhibitors (TKIs) often interact with the multidrug resistant (MDR) phenotype of cancer cells. In some cases, TKIs increase the susceptibility of MDR cancer cells to chemotherapy. As the overexpression of membrane transporter P‐glycoprotein (P‐gp) is the most com-mon alteration in MDR cancer cells, we investigated the effects of...

Uploaded on: March 27, 2023
2017 (v1)

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Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists.

Giacchello I. Musumeci F. Greco C.

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Uploaded on: April 14, 2023
2020 (v1)

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Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana

Bisio A. Schito A. M. Pedrelli F.

A surface extract of the aerial parts of Salvia tingitana afforded a nor-sesterterpenoid (1) and eight new sesterterpenoids (2-̵9), along with five known sesterterpenoids, five labdane and one abietane diterpenoid, one sesquiterpenoid, and four flavonoids. The structures of the new compounds were established by 1D and 2D NMR spectroscopy,...

Uploaded on: April 14, 2023