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2013 (v1)PublicationUploaded on: March 31, 2023
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2009 (v1)Publication
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2005 (v1)Publication
The presence in Paramecium of gamma-aminobutyric acid A-type receptors (GABA(A)) and the capability of the protozoon to synthesize and release the GABA neurotransmitter into the environment have already been demonstrated. This study investigates the involvement of the GABA(A) complex in the swimming control of the ciliated protozoon. The...
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2012 (v1)Publication
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2013 (v1)Publication
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2006 (v1)Publication
Multi-photon excitation (MPE) microscopy plays a growing role among microscopical techniques utilized for studying biological matter. In conjunction with confocal microscopy it can be considered the imaging workhorse of life science laboratories. Its roots can be found in a fundamental work written by Maria Goeppert Mayer more than 70 years...
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2006 (v1)Publication
Nowadays, optical microscopy has evolved into three‐dimensional (3‐D) (x‐y‐z) and four‐dimensional (4‐D) (x‐y‐z‐t) analyses allowing researchers to probe even deeper into the intricate mechanisms of living systems. Within this scenario, two‐photon and multiphoton excitation (TPE, MPE) microscopy are probably the most relevant advancement in...
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2006 (v1)Publication
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2009 (v1)Publication
The effect of euplotin C-a cytotoxic secondary metabolite produced by the protist ciliate Euplotes crassus-on the voltage-dependent Ca(2+) channel activity was studied in a single-celled system by analyzing the swimming behavior of Paramecium. When the intraciliary Ca(2+) concentration associated with plasma membrane depolarization increases, a...
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2015 (v1)Publication
Fanconi Anemia (FA) is a rare and complex inherited blood disorder associated with bone marrow failure and malignancies. Many alterations in FA physiology appear linked to red-ox unbalance including alterations in the morphology and structure of nuclei, intermediate filaments and mitochondria, defective respiration, reduced ATP production and...
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2003 (v1)Publication
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2016 (v1)Publication
Glutamate (Glu) excitotoxicity plays a major role in amyotrophic lateral sclerosis (ALS) and elevated extracellular Glu levels were found in patients and animal models of the disease. Reduced astrocyte uptake was suggested as the main cause for increased Glu availability. On the basis of our experiments, we postulated that abnormal...
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2015 (v1)Publication
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Uploaded on: April 14, 2023 -
2004 (v1)Publication
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Uploaded on: March 31, 2023