Granulocyte and monocyte apheresis has been used in different immune-mediated disorders, mainly inflammatory bowel diseases. The removal of activated leukocytes and several additional immunomodulatory mechanisms have been so far suggested to explain the anti-inflammatory effects of the treatment. Recent data indicate that, during centrifugation...
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2017 (v1)PublicationUploaded on: April 14, 2023
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2023 (v1)Publication
BackgroundNatural Killer cells (NKs) represent the innate counterpart of TCR & alpha;& beta; lymphocytes and are characterized by a high anti-tumor and an anti-viral cytotoxic activity. Recently, it has been demonstrated that NKs can express PD-1 as an additional inhibitory receptor. Specifically, PD-1 was identified on a subpopulation of...
Uploaded on: January 31, 2024