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UHRHAMMER , Nancy

Last name: UHRHAMMER

First name: Nancy

February 3, 2015 (v1)

Journal article

Metadata-only

Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation

Denizot, Jérémy Desrichard, Alexis Agus, Allison

Objective Adherent-invasive Escherichia coli (AIEC) are abnormally predominant on Crohn's disease (CD) ileal mucosa. AIEC strains adhere to enterocytes via interaction between type 1 pili and CEACAM6 receptors abnormally expressed on CD ileal mucosa, leading to gut inflammation. We analysed whether epigenetic mechanisms are involved in the...

Uploaded on: December 4, 2022