2010 (v1)
Publication
Evidence indicates that endosomal entry promotes signaling by the Notch receptor, but the mechanisms involved are not clear. In a search for factors that regulate Notch activation in endosomes, we isolated mutants in Drosophila genes that encode subunitsof the vacuolar ATPase (V-ATPase) proton pump. Cells lacking V-ATPase function display...
Uploaded on: May 12, 2023