VENTURINI , Pier Luigi

Importance of the field: Medical therapy is the most commonly used treatment for endometriosis. In particular, the administration of hormonal therapies aims to improve symptoms with minimal adverse effects. Areas covered in this review: Observational and randomized studies evaluating the efficacy of medical therapy on symptoms associated with...

INTRODUCTION: Ectopic endometrial tissue is found in 1.5% to 6.2% of women of reproductive age, in up to 60% of those with dysmenorrhoea, and in up to 30% of women with subfertility, with a peak incidence at around 40 years of age. However, symptoms may not correlate with laparoscopic findings. METHODS AND OUTCOMES: We conducted a systematic...

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Endometriosis is a chronic disease that causes pain and infertility. Combined oral contraceptives and progestins are commonly used for the treatment of endometriosis because they reduce the severity of pain symptoms in 60–70% of patients and are well tolerated. Gonadotropin-releasing hormone analogs and danazol may be administered to selected...

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Evaluate patient satisfaction at 6-month treatment in women with symptomatic rectovaginal endometriosis and migraine without aura with (progestogen-only contraceptive pill, POP versus sequential combined oral contraceptives, COC) STUDY DESIGN: A patient preference trial including 144 women (82 in the group COC and 62 in the group POP). Main...

Ectopic endometrial tissue is found in 2% to 6% of women of reproductive age, in up to 60% of those with dysmenorrhoea, and in up to 30% of women with subfertility, with a peak incidence at around 40 years of age. However, symptoms may not correlate with laparoscopic findings.

BACKGROUND: Aromatase inhibitors have recently been proposed for the treatment of endometriosis; however, no previous study examined the effects of these agents on pain and urinary symptoms of premenopausal women with bladder endometriosis. CASE: Two premenopausal patients with bladder endometriosis were treated with letrozole (2.5 mg/day),...

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Objective: To evaluate the effectiveness of treatment with vaginal danazol in improving the pain symptoms caused by rectovaginal endometriosis that persist after insertion of a levonorgestrel-releasing intrauterine device (LNG-IUD). Methods: This pilot observational study included 15 women with rectovaginal endometriosis and pain symptoms...

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PURPOSE: This study aims to present the clinical characteristics of a series of postmenopausal women with endometriosis and to evaluate the preferential location, extension and histopathological features of the lesions. METHODS: We retrospectively examined the clinical records of 72 postmenopausal women with endometriosis who underwent surgery...

Study Objective: To assess the efficacy of periurethral injections (PIs) of polyacrylamide hydrogel (PAHG, Bulkamid) for the treatment of recurrent stress urinary incontinence (rSUI) in women previously treated with midurethral sling procedures. Design: This prospective study included women with rSUI. The International Consultation on...

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Current treatment of endometriosis is mainly based on surgery and ovarian suppressive agents. In the last 10 years, it has been demonstrated that aromatase P450, a key enzyme for estrogen biosynthesis, may have a pathogenic role in endometriosis because it is aberrantly expressed in endometriotic implants and in eutopic endometrium of women...

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This systematic review aims to assess the efficacy of aromatase inhibitors (AIs) in treating pain symptoms caused by endometriosis. A comprehensive literature search was conducted to identify all the published studies evaluating the efficacy of type II nonsteroidal aromatase inhibitors (anastrozole and letrozole) in treating...

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