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1996 (v1)PublicationUploaded on: March 27, 2023
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1993 (v1)Publication
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2013 (v1)Publication
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2015 (v1)Publication
Rapid advances in the genetics of amyotrophic lateral sclerosis (ALS) have dramatically changed the approach of clinicians and researchers to the motor neuron diseases. We report two siblings in whom the genetic study provided conflicting results, hence raising a number of issues which deserve to be considered by clinicians involved in genetic...
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2013 (v1)Publication
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2012 (v1)Publication
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1996 (v1)Publication
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1995 (v1)Publication
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2002 (v1)Publication
Background: The traditional exact method for inferring relationships between individuals from genetic data is not easily applicable in all situations that may be encountered in several fields of applied genetics. This study describes an approach that gives affordable results and is easily applicable; it is based on the probabilities that two...
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2013 (v1)Publication
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Uploaded on: March 27, 2023 -
2012 (v1)Publication
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2015 (v1)Publication
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1992 (v1)Publication
This study was designed to identify the target molecules of the natural killer (NK) cell-mediated recognition of normal allogeneic target cells. As previously shown, the gene(s) governing the first NK-defined allospecificity (specificity 1) were found to be localized in the major histocompatibility complex region between BF gene and HLA-A. In...
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1991 (v1)Publication
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1996 (v1)Publication
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1995 (v1)Publication
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2002 (v1)Publication
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1998 (v1)Publication
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2010 (v1)Publication
Abstract A total of 46 patients with primary myelofibrosis (PMF) (median age 51 years), underwent an allogeneic hemopoietic SCT (HSCT) after a thiotepa-based reducedintensity conditioning regimen. The median follow-up for surviving patients is 3.8 years. In multivariate analysis, independent unfavorable factors for survival were RBC...
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2000 (v1)Publication
Purpose: To investigate the use of a nonmyeloablative fludarabine-based immunosuppressive regimen to allow engraftment of HLA-sibling donors' mobilized stem cells and induction of a graft-versus-lymphoma effect for patients with advanced resistant Hodgkin's disease and non-Hodgkin's lymphoma. Patients and Methods: Fifteen patients with...
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2016 (v1)Publication
Genetic discoveries in amyotrophic lateral sclerosis (ALS) have a significant impact on deciphering molecular mechanisms of motor neuron degeneration but, despite recent advances, the etiology of most sporadic cases remains elusive. Several cellular mechanisms contribute to the motor neuron degeneration in ALS, including RNA metabolism,...
Uploaded on: April 14, 2023