V

VITALE M

Last name: VITALE M

2004 (v1)

Publication

Metadata-only

CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells.

SIVORI, SIMONA DELLA CHIESA, MARIELLA CARLOMAGNO, SIMONA

Toll-like receptors (TLRs) are pattern-recognition receptors responsible for triggering cells of innate immunity. In this study we investigated the expression and function of TLRs 3 and 9 in human natural killer (NK) cells. In the presence of IL-12, freshly isolated NK cells responded to double-stranded RNA or unmethylated CpG DNA and expressed...

Uploaded on: April 14, 2023