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VAALAND , I. Caroline

Last name: VAALAND

First name: I. Caroline

September 11, 2023 (v1)

Publication

Metadata-only

Investigation of the Enantioselectivity of Acetylcholinesterase and Butyrylcholinesterase upon Inhibition by Tacrine-iminosugar Heterodimers

Vaaland, I. Caroline López López, Óscar Puerta, Adrián

The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric pairs of heterodimers containing a tacrine residue and a 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) or 1,4-dideoxy-1,4-imino-L-arabinitol (LAB) moiety held together via linkers of variable lengths containing a 1,2,3-triazole ring and 3, 4, or 7 CH2 groups....

Uploaded on: October 11, 2023