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VAGNER , Stéphan

Last name: VAGNER

First name: Stéphan

May 27, 2021 (v1)

Publication

Metadata-only

BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair

Sessa, Gaetana Gómez González, Belén María Silva, Sonia

The BRCA2 tumor suppressor is a DNA double-strand break (DSB) repair factor essential for maintaining genome integrity. BRCA2-deficient cells spontaneously accumulate DNA-RNA hybrids, a known source of genome instability. However, the specific role of BRCA2 on these structures remains poorly understood. Here we identified the DEAD-box RNA...

Uploaded on: December 1, 2022
December 2018 (v1)

Journal article

Metadata-only

Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma

Cerezo, Michael Guemiri, Ramdane Druillennec, Sabine

International audience

Uploaded on: December 4, 2022