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VAN WERKHOVEN , C. H.

Last name: VAN WERKHOVEN

First name: C. H.

October 24, 2022 (v1)

Publication

Metadata-only

Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics

Van Werkhoven, C. H. Ducher, A. Berkell, M.

Trial enrichment using gut microbiota derived biomarkers by high-risk individuals can improve the feasibility of randomized controlled trials for prevention of Clostridioides difficile infection (CDI). Here, we report in a prospective observational cohort study the incidence of CDI and assess potential clinical characteristics and biomarkers to...

Uploaded on: December 4, 2022
April 19, 2023 (v1)

Publication

Metadata-only

Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group

Schweitzer, V. A. Van Werkhoven, C. H. Bielicki, J.

Background Antimicrobial stewardship interventions and programmes aim to ensure effective treatment while minimizing antimicrobial-associated harms including resistance. Practice in this vital area is undermined by the poor quality of research addressing both what specific antimicrobial use interventions are effective and how antimicrobial use...

Uploaded on: April 20, 2023