V

M

VASSALLI , M

Last name: VASSALLI

First name: M

2022 (v1)

Publication

Metadata-only

Cellular Mechanosensitivity: Validation of an Adaptable 3D-Printed Device for Microindentation

Capponi, G Zambito, M Neri, I

Mechanotransduction refers to the cellular ability to sense mechanical stimuli from the surrounding environment and convert them into biochemical signals that regulate cellular physiology and homeostasis. Mechanosensitive ion channels (MSCs), especially ones of Piezo family (Piezo1 and Piezo2), play a crucial role in mechanotransduction. These...

Uploaded on: February 4, 2024
2014 (v1)

Publication

Metadata-only

Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements

Corsaro, A Raccosta, S De Stefano, S

No description

Uploaded on: April 14, 2023
2013 (v1)

Publication

Metadata-only

Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment

THELLUNG, STEFANO GATTA, ELENA PELLISTRI, FRANCESCA

Prion diseases recognize, as a unique molecular trait, the misfolding of CNS-enriched prion protein (PrP(C)) into an aberrant isoform (PrP(Sc)). In this work, we characterize the in vitro toxicity of amino-terminally truncated recombinant PrP fragment (amino acids 90-231, PrP90-231), on rat cerebellar granule neurons (CGN), focusing on...

Uploaded on: April 14, 2023