V

J

VELDEN , Jeroen Van Der

Last name: VELDEN

First name: Jeroen Van Der

August 21, 2017 (v1)

Publication

Metadata-only

Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

Toscano, Miguel G. Velden, Jeroen van der Werf, Sybrand van der

Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products in humans. However, the clinical use of SV40 vectors has been hampered by the lack of a...

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