BACKGROUND: Psychotropic drugs are frequently prescribed in nursing homes (NH). Nonetheless, we hoped that institutionalization decreases the number of psychotropic drug classes prescribed, because NH residents may have more psychosocial interventions than patients living at home.OBJECTIVE: The aim was to compare the type and number of...
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2016 (v1)Journal articleUploaded on: February 28, 2023
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March 24, 2014 (v1)Journal article
Alzheimer's disease and other related disorders (ADRD) represent a major challenge for health care systems within the aging population. It is therefore important to develop better instruments to assess the disease severity and progression, as well as to improve its treatment, stimulation, and rehabilitation. This is the underlying idea for the...
Uploaded on: March 25, 2023 -
2012 (v1)Journal article
Abstract: Biomarkers have gained an increased importance in the past years in helping physicians to diagnose Alzheimer's disease (AD). This study was designed to identify a blood-based, transcriptomic signature that can differentiate AD patients from control subjects. The performance of the signature was then evaluated for robustness in an...
Uploaded on: February 28, 2023 -
September 13, 2019 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
2019 (v1)Publication
BACKGROUND: Biomarker-based risk predictions of dementia in people with mild cognitive impairment are highly relevant for care planning and to select patients for treatment when disease-modifying drugs become available. We aimed to establish robust prediction models of disease progression in people at risk of dementia. METHODS: In this...
Uploaded on: April 14, 2023 -
2020 (v1)Journal article
Introduction: Subjective cognitive complaints may be a signature of preclinical stage Alzheimer's disease. However, the link between subjective cognitive and non‐cognitive complaints and brain alterations remains unclear.Methods: The relationship between cognitive and non‐cognitive complaints and brain biomarkers, measured by structural...
Uploaded on: December 3, 2022 -
2018 (v1)Journal article
IntroductionThe free and cued selective reminding test is used to identify memory deficits in mild cognitive impairment and demented patients. It allows assessing three processes: encoding, storage, and recollection of verbal episodic memory.MethodsWe investigated the neural correlates of these three memory processes in a large cohort study....
Uploaded on: December 4, 2022