Little is known about the physiological role of the phospholipase A2 receptor (PLA2R1). PLA2R1 has been described as regulating the replicative senescence, a telomerase-dependent proliferation arrest. The downstream PLA2R1 signaling and its role in cancer are currently unknown. Senescence induction in response to activated oncogenes is a...
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October 14, 2013 (v1)Journal articleUploaded on: December 4, 2022
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December 2020 (v1)Journal article
Background: Undifferentiated pleomorphic sarcoma (UPS) is the most frequent, aggressive and less-characterized sarcoma subtype. This study aims to assess UPS molecular characteristics and identify specific therapeutic targets. Methods: High-throughput technologies encompassing immunohistochemistry, RNA-sequencing, whole exomesequencing, mass...
Uploaded on: December 4, 2022