V

VERCELLINO M

Last name: VERCELLINO M

2018 (v1)

Publication

Metadata-only

Overexpression of sphingosine-1-phosphate receptors on reactive astrocytes drives neuropathology of multiple sclerosis rebound after fingolimod discontinuation

Giordana MT Cavalla P Uccelli A

We present the neuropathological description of an autoptic case of fatal rebound of disease activity after fingolimod discontinuation in a multiple sclerosis patient. MRI prior to the fatal outcome showed several large tumefactive demyelinating lesions. These lesions were characterized by prominent astrocytic gliosis, with a remarkable...

Uploaded on: April 14, 2023