Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in industrialized countries and is associated with increased risk of cardiovascular, hepatic and metabolic diseases. Molecular mechanisms on the root of the disrupted lipid homeostasis in NAFLD and potential therapeutic strategies can benefit of in vivo and in vitro...
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2017 (v1)PublicationUploaded on: April 14, 2023
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2015 (v1)Publication
Hierarchical materials are abundantly found in nature, and recently object of biomimetic and engineering research studies. Indeed, the fascinating mechanisms behind the outstanding mechanical properties of natural materials inspire many researchers to deeply investigate such materials, with the goal of designing and manufacturing new materials...
Uploaded on: April 14, 2023 -
2019 (v1)Publication
Delamination is the major failure mechanism in composite laminates and eventually leads to material failure. An early-detection and a better understanding of this phenomenon, through non-destructive assessment, can provide a proper in situ repair and allow a better evaluation of its effects on residual strength of lightweight structural...
Uploaded on: April 14, 2023 -
2005 (v1)Publication
Metallothioneins (MTs) are noncatalytic peptides involved in storage of essential ions, detoxification of nonessential metals, and scavenging of oxyradicals. They exhibit an unusual primary sequence and unique 3D arrangement. Whereas vertebrate MTs are characterized by the well-known dumbbell shape, with a β domain that binds three bivalent...
Uploaded on: February 14, 2024 -
2020 (v1)Publication
Bone quantity and quality are considered the main predictors of bone mechanical properties (i.e., strength and fracture resistance). These factors deal with the morphology and chemical composition of bone and can be assessed by non-invasive techniques such as dual-energy x-ray absorptiometry (DXA), providing the bone mineral density (BMD) and...
Uploaded on: April 14, 2023 -
1987 (v1)Publication
A pigment made up of a protein able to bind retinal as well as retinol is described. The molecule consists of a dimer with a molecular weight of 50,000 which binds one molecule of retinal. The binding site for retinal is a Schiff base buried in the interior of the protein. Retinol is probably bound to the protein in the same site as for...
Uploaded on: July 3, 2024