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VILALTA , Anna

Last name: VILALTA

First name: Anna

October 16, 2018 (v1)

Publication

Metadata-only

Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation

Carrillo Jiménez, Alejandro Puigdellívol, Mar Vilalta, Anna

Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer's disease (AD). The use of primary microglial cell cultures has proved to be a valuable tool to study microglial biology under various conditions. However, more advanced transfection methodologies for...

Uploaded on: March 27, 2023
February 24, 2017 (v1)

Publication

Metadata-only

Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration

Kei Yip, Ping Carrillo Jiménez, Alejandro King, Paul

Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an estimate of 2.5 million people affected per year in Europe, indicating the need for advances in TBI treatment. Within the first 24 h after TBI, several inflammatory response factors become upregulated, including the lectin...

Uploaded on: March 27, 2023