V

VILLA V.

Last name: VILLA V.

2010 (v1)

Publication

Metadata-only

Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability

Thellung S. Corsaro A. Villa V.

No description

Uploaded on: March 31, 2023
2022 (v1)

Publication

Metadata-only

A New Bistable Switch Model of Alzheimer's Disease Pathogenesis

Burlando B. Losacco S. Villa V.

We propose a model to explain the pathogenesis of Alzheimer's disease (AD) based on the theory that any disease affecting a healthy organism originates from a bistable feedback loop that shifts the system from a physiological to a pathological condition. We focused on the known double inhibitory loop involving the cellular prion protein (PrPC)...

Uploaded on: February 14, 2024
2012 (v1)

Publication

Metadata-only

Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity

Corsaro A. Thellung S. Villa V.

Transmissible spongiform encephalopathies (TSE), or prion diseases, are a group of fatal neurodegenerative disorders of animals and humans. Human diseases include Creutzfeldt-Jakob (CJD) and Gerstmann-Straussler-Scheinker (GSSD) diseases, fatal familial insomnia, and Kuru. Human and animal TSEs share a common histopathology with a pathognomonic...

Uploaded on: February 4, 2024