V

B

VIOLLET , Benoit

Last name: VIOLLET

First name: Benoit

December 6, 2019 (v1)

Journal article

Metadata-only

Editorial: Metformin: Beyond Diabetes

Bost, Frédéric Rena, Graham Viollet, Benoit

International audience

Uploaded on: December 4, 2022
May 20, 2015 (v1)

Journal article

Metadata-only

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of ras-transformed fibroblasts

Pelletier, Joffrey Roux, Danièle Viollet, Benoit

AbstrAct Lactic acid generated by highly glycolytic tumours is exported by the MonoCarboxylate Transporters, MCT1 and MCT4, to maintain pHi and energy homeostasis. We report that MCT1 inhibition combined with Mct4 gene disruption severely reduced glycolysis and tumour growth without affecting ATP levels. Because of the key role of the...

Uploaded on: March 26, 2023