In this study, we describe a novel activating transcription factor 3 (ATF3)-dependent death pathway triggered by ultraviolet (UV) irradiation. We demonstrate that ATF3 contributes to UV-induced apoptosis through the regulation of hypoxia inducible factor (Hif)-2alpha expression, which in turn induces the expression of proapoptotic genes, such...
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September 2008 (v1)Journal articleUploaded on: December 4, 2022
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August 19, 2008 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
2005 (v1)Journal article
No description
Uploaded on: December 3, 2022 -
August 5, 2013 (v1)Journal article
: Glioblastoma multiforme (GBM) are highly invasive and angiogenic malignancies with a median survival time from diagnosis of <15 months. Previous work has revealed robust overexpression of fibronectin (FN) mRNA in GBM, although immunohistochemical staining of FN in these tumors is typically associated with the angiogenic vasculature. Here we...
Uploaded on: December 2, 2022 -
2005 (v1)Journal article
No description
Uploaded on: October 11, 2023 -
August 5, 2013 (v1)Journal article
: Glioblastoma multiforme (GBM) are highly invasive and angiogenic malignancies with a median survival time from diagnosis of <15 months. Previous work has revealed robust overexpression of fibronectin (FN) mRNA in GBM, although immunohistochemical staining of FN in these tumors is typically associated with the angiogenic vasculature. Here we...
Uploaded on: October 11, 2023