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VLACHOS , Ioannis

Last name: VLACHOS

First name: Ioannis

July 19, 2023 (v1)

Journal article

Metadata-only

Identifying and profiling structural similarities between Spike of SARS-CoV-2 and other viral or host proteins with Machaon

Kakoulidis, Panos Vlachos, Ioannis Thanos, Dimitris

Using protein structure to predict function, interactions, and evolutionary history is still an open challenge, with existing approaches relying extensively on protein homology and families. Here, we present Machaon, a data-driven method combining orientation invariant metrics on phi-psi angles, inter-residue contacts and surface complexity. It...

Uploaded on: December 8, 2023