Enhanced glucose utilization can be visualized in atherosclerotic lesions and may reflect a high glycolytic rate in lesional macrophages, but its causative role in plaque progression remains unclear. We observe that the activity of the carbohydrate-responsive element binding protein ChREBP is rapidly downregulated upon TLR4 activation in...
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October 2015 (v1)Journal articleUploaded on: December 3, 2022
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April 2016 (v1)Journal article
Rationale: Inflamed atherosclerotic plaques can be visualized by noninvasive positron emission and computed tomographic imaging with 18 F-fluorodeoxyglucose, a glucose analog, but the underlying mechanisms are poorly understood. Objective: Here, we directly investigated the role of Glut1-mediated glucose uptake in apolipoprotein E–deficient (...
Uploaded on: December 4, 2022 -
October 2015 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
October 2015 (v1)Journal article
International audience
Uploaded on: February 22, 2023 -
April 2016 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
April 2016 (v1)Journal article
International audience
Uploaded on: February 22, 2023 -
October 6, 2015 (v1)Journal article
Enhanced glucose utilization can be visualized in atherosclerotic lesions and may reflect a high glycolytic rate in lesional macrophages, but its causative role in plaque progression remains unclear. We observe that the activity of the carbohydrate-responsive element binding protein ChREBP is rapidly downregulated upon TLR4 activation in...
Uploaded on: February 28, 2023 -
June 1, 2023 (v1)Journal article
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Uploaded on: November 27, 2023