W

J

WILCE , Jacqueline A.

Last name: WILCE

First name: Jacqueline A.

August 30, 2022 (v1)

Publication

Metadata-only

Regulation of TIA-1 Condensates: Zn2+ and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation

West, Danella L. Loughlin, Fionna E. Rivero Rodríguez, Francisco

Stress granules are non-membrane bound RNA-protein granules essential for survival during acute cellular stress. TIA-1 is a key protein in the formation of stress granules that undergoes liquid-liquid phase separation by association with specific RNAs and protein-protein interactions. However, the fundamental properties of the TIA-1 protein...

Uploaded on: March 25, 2023