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WILLCOCKS , Isabella R.

Last name: WILLCOCKS

First name: Isabella R.

November 22, 2022 (v1)

Publication

Metadata-only

Interaction testing and polygenic risk scoring to estimate the association of common genetic variants with treatment resistance in schizophrenia

Pardiñas, Antonio F. Smart, Sophie E. Willcocks, Isabella R.

Importance About 20% to 30% of people with schizophrenia have psychotic symptoms that do not respond adequately to first-line antipsychotic treatment. This clinical presentation, chronic and highly disabling, is known as treatment-resistant schizophrenia (TRS). The causes of treatment resistance and their relationships with causes underlying...

Uploaded on: March 24, 2023