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WONG , Priscilla C H

Last name: WONG

First name: Priscilla C H

2022 (v1)

Publication

Metadata-only

Jagged Ends on Multinucleosomal Cell-Free DNA Serve as a Biomarker for Nuclease Activity and Systemic Lupus Erythematosus

Ding, Spencer C Chan, Rebecca W Y Peng, Wenlei

Background Jagged ends of plasma DNA are a recently recognized class of fragmentomic markers for cell-free DNA, reflecting the activity of nucleases. A number of recent studies have also highlighted the importance of jagged ends in the context of pregnancy and oncology. However, knowledge regarding the generation of jagged ends is incomplete....

Uploaded on: February 4, 2024