WOOLFORD , John L.

Last name: WOOLFORD

First name: John L.

August 8, 2016 (v1)

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Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function

Babiano González, Reyes Gamalinda, Michael Woolford, John L.

Ribosomal proteins play important roles in ribosome biogenesis and function. Here, we study the evolutionarily conserved L26 inSaccharomyces cerevisiae, which assembles into pre-60S ribosomal particles in the nucle(ol)us. Yeast L26 is one of the many ribosomal proteins encoded by two functional genes. We have disrupted both genes; surprisingly,...

Uploaded on: March 27, 2023
March 3, 2015 (v1)

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Yeast Polypeptide Exit Tunnel Ribosomal Proteins L17, L35, and L37 are Necessary to Recruit Late-assembling Factors Required for 27SB Pre-rRNA Processing

Woolford, John L. Babiano González, Reyes Cruz Díaz, Jesús de la

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Uploaded on: March 25, 2023
July 11, 2022 (v1)

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Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation

Micic, Jelena Rodríguez Galán, Olga Babiano González, Reyes

During translation, nascent polypeptide chains travel from the peptidyl transferase center through the nascent polypeptide exit tunnel (NPET) to emerge from 60S subunits. The NPET includes portions of five of the six 25S/5.8S rRNA domains and ribosomal proteins uL4, uL22, and eL39. Internal loops of uL4 and uL22 form the constriction sites of...

Uploaded on: December 4, 2022

WOOLFORD , John L.

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