Y
J
Last name: YANG
First name: Jimin
International audience
A network dependency platform was generated to define a landscape of cancer drug mechanisms in pulmonary hypertension.
A network dependency platform was generated to define a landscape of cancer drug mechanisms in pulmonary hypertension.
Cancer therapies are being considered for treating rare noncancerous diseases like pulmonary hypertension (PH), but effective computational screening is lacking. Via transcriptomic differential dependency analyses leveraging parallels between cancer and PH, we mapped a landscape of cancer drug functions dependent upon rewiring of PH gene...