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ZAMPELLI , Angela

Last name: ZAMPELLI

First name: Angela

2022 (v1)

Publication

Metadata-only

Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies

Akwa, Yvette Di Malta, Chiara Zallo, Fátima

Synapses represent an important target of Alzheimer disease (AD), and alterations of their excitability are among the earliest changes associated with AD development. Synaptic activation has been shown to be protective in models of AD, and deep brain stimulation (DBS), a surgical strategy that modulates neuronal activity to treat neurological...

Uploaded on: January 28, 2024