ZANARDI , Ilaria

Nickel (Ni2+) is a toxic metal that affects the function of several neuronal ionic channels. Ni2+ inhibits N-methyl-d-aspartate receptor (NR) channel in a voltage-dependent manner, but also causes enhancement of NR2B-containing channel activity and voltage-independent inhibition of those containing NR2A. The present work was aimed to find the...

• Ion transport proteins in intracellular membranes of eukaryotic cells play key roles in many physiological and pathological processes. • The function of many of these transporters is poorly understood, because their intracellular localization makes them difficult to study. • Here, we used the large organelle of plant cells, the central...