Hypertrophic chondrocytes have important roles in promoting invasion of cartilage by blood vessels and its replacement with bone. However, it is unclear whether blood vessels exert reciprocal positive influences on chondrocyte maturation and function. Therefore, we implanted beads containing the antiangiogenic molecule squalamine around humeral...
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2002 (v1)PublicationAntiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesisUploaded on: April 14, 2023
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2023 (v1)Publication
Natural aminosterols are promising drug candidates against neurodegenerative diseases, like Alzheimer and Parkinson, and one relevant protective mechanism occurs via their binding to biological membranes and displacementor binding inhibition of amyloidogenic proteins and their cytotoxic oligomers. We compared three chemically different...
Uploaded on: February 6, 2024