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ZHANG , Xianqin

Last name: ZHANG

First name: Xianqin

2015 (v1)

Publication

Metadata-only

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

Zhang, Xianqin Bogunovic, Dusan Payelle-Brogard, Béatrice

Intracellular ISG15 is an interferon (IFN)-α/β-inducible ubiquitinlike modifier which can covalently bind other proteins in a process called ISGylation; it is an effector of IFN-α/β-dependent antiviral immunity in mice. We previously published a study describing humans with inherited ISG15deficiency but without unusually severe viral diseases....

Uploaded on: April 14, 2023