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ZUCCHI , Ileana

Last name: ZUCCHI

First name: Ileana

2020 (v1)

Publication

Metadata-only

Integrating Microstructured Electrospun Scaffolds in an Open Microfluidic System for in Vitro Studies of Human Patient-Derived Primary Cells

Guida, Patrizia Piscitelli, Eleonora Marrese, Marica

Recent studies have suggested that microenvironmental stimuli play a significant role in regulating cellular proliferation and migration, as well as in modulating self-renewal and differentiation processes of mammary cells with stem cell (SCs) properties. Recent advances in micro/nanotechnology and biomaterial synthesis/engineering currently...

Uploaded on: March 27, 2023
2024 (v1)

Publication

Metadata-only

Long-term culture of patient-derived mammary organoids in non-biogenic electrospun scaffolds for identifying metalloprotein and motor protein activities in aging and senescence

Piscitelli, Eleonora Maya, Iriczalli Cruz Cocola, Cinzia

We recently identified TMEM230 as a master regulator of the endomembrane system of cells. TMEM230 expression is necessary for promoting motor protein dependent intracellular trafficking of metalloproteins for cellular energy production in mitochondria. TMEM230 is also required for transport and secretion of metalloproteinases for autophagy and...

Uploaded on: July 3, 2024