Macrophage metabolic regulation in atherosclerotic plaque

Creators: Dolfi, Bastien; Gallerand, Alexandre; Haschemi, Arvand; Guinamard, Rodolphe r.; Ivanov, Stoyan

Others:: Centre méditerranéen de médecine moléculaire (C3M) ; Université Nice Sophia Antipolis (1965 - 2019) (UNS) ; COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA); Medizinische Universität Wien = Medical University of Vienna; Centre National de la Recherche Scientifique (CNRS); Laboratoire de PhysioMédecine Moléculaire (LP2M) ; Université Nice Sophia Antipolis (1965 - 2019) (UNS) ; COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)

Description

Metabolism plays a key role in controlling immune cell functions. In this review, we will discuss the diversity of plaque resident myeloid cells and will focus on their metabolic demands that could reflect on their particular intraplaque localization. Defining the metabolic configuration of plaque resident myeloid cells according to their topologic distribution could provide answers to key questions regarding their functions and contribution to disease development.

Abstract

International audience

Macrophage metabolic regulation in atherosclerotic plaque

Description

Abstract

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