Published May 30, 2023 | Version v1
Publication

Compartmentalization, a key mechanism controlling the multi-tasking role of SnRK1 complex

Citation

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Description

SNF1-related protein kinase 1 (SnRK1), the plant ortholog of mammalian AMP-activated protein kinase/fungal (yeast) Sucrose Non-Fermenting 1 (AMPK/SNF1), plays a central role in metabolic responses to reduced energy levels in response to nutritional and environmental stresses. SnRK1 functions as a heterotrimeric complex composed of a catalytic α- and regulatory β- and βγ-subunits. SnRK1 is a multitasking protein involved in regulating various cellular functions, including growth, autophagy, stress response, stomatal development, pollen maturation, hormone signaling, and gene expression. However, little is known about the mechanism whereby SnRK1 ensures differential execution of downstream functions. Compartmentalization has been recently proposed as a new key mechanism for regulating SnRK1 signaling in response to stimuli. In this review, we discuss the multitasking role of SnRK1 signaling associated with different subcellular compartments.

Abstract

Ministerio de Ciencia e Innovación y Agencia Estatal de Investigación, de España (MCIN/AEI) PID2020-119737GA-I00

Abstract

Ministerio de Economía y Competitividad de España - PGC2018-099048-B-100

Additional details

Created:
May 31, 2023
Modified:
November 28, 2023