Published May 23, 2022
| Version v1
Publication
Improving the Efficiency of MECoMaP: A Protein Residue-Residue Contact Predictor
Description
This work proposes an improvement of the multi-objective
evolutionary method for the protein residue-residue contact prediction
called MECoMaP. This method bases its prediction on physico chemical properties of amino acids, structural features and evolutionary
information of the proteins. The evolutionary algorithm produces a set
of decision rules that identifies contacts between amino acids. These
decision rules generated by the algorithm represent a set of conditions to
predict residue-residue contacts. A new encoding used, a fast evaluation
of the examples from the training data set and a treatment of unbalanced
classes of data were considered to improve the the efficiency of the
algorithm.
Additional details
Identifiers
- URL
- https://idus.us.es/handle//11441/133513
- URN
- urn:oai:idus.us.es:11441/133513