SECONDARY METABOLITES FROM SALVIA TINGITANA ETL. (LAMIACEAE).

In the course of our study on Salvia species for the identification of potential new crops with diversified value in the Mediterranean agriculture(1-3), we considered Salvia tingitana Etl. The species is a perennial shrub original from the Arabian region (4) and cultivated as an ornamental plant. The surface extract, obtained by rinsing the fresh aerial parts with CH2Cl2 was subjected to repeated column chromatography on Sephadex LH-20, silica gel, SPE separations and to semi-preparative RP-HPLC, and afforded four diterpenes and five known sesterterpenes, along with one new labdane diterpene (1) and three new sesterterpenes (2-4), identified by IR, NMR, including TOCSY, COSY, HSQC, HMBC and ROESY experiments, ESI-MS and HR-MS analysis.