Published May 20, 2021
| Version v1
Publication
Stress and inflammation: a detrimental combination in the development of neurodegenerative disease
Description
Chronic stress accelerates the appearance of some neurodegenerative disorders, such as Alzheimer's disease
and Parkinson´s disease. On this review we firstly, describe some human epidemiological studies that highlight
the possibility that chronic stress could increase the incidence or the rate of incidence of Alzheimer's disease
and Parkinson´s disease. Secondly, we discuss the important role of inflammation in the progression and
development of these neurodegenerative diseases. Finally, we try to justify the relationship between stress and
inflammation with some experimental data. This work strongly suggests that chronic stress could be considered
a key factor for the development of neurodegenerative diseases through microglial activation.
Additional details
Identifiers
- URL
- https://idus.us.es/handle//11441/109097
- URN
- urn:oai:idus.us.es:11441/109097