The long and short of membrane fission.

Creators: Roux, Aurélien; Antonny, Bruno

Others:: Physico-Chimie-Curie (PCC) ; Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut Curie [Paris]-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS); Institut de pharmacologie moléculaire et cellulaire (IPMC) ; Université Nice Sophia Antipolis (1965 - 2019) (UNS) ; COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)

Description

During membrane fission, the GTPase dynamin forms helical assemblies at the neck of membrane buds. Although it has been proposed that fission results from the constriction of the dynamin helix, new work by Bashkirov et al. (2008) and Pucadyil and Schmid (2008) unexpectedly shows that helix disassembly is also necessary for membrane fission.

Abstract

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The long and short of membrane fission.

Description

Abstract

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