Published July 21, 2022
| Version v1
Publication
Discovering α–patterns from gene expression data
Description
The biclustering techniques have the purpose of finding subsets of
genes that show similar activity patterns under a subset of conditions. In this
paper we characterize a specific type of pattern, that we have called α–pattern,
and present an approach that consists in a new biclustering algorithm specifically
designed to find α–patterns, in which the gene expression values evolve across
the experimental conditions showing a similar behavior inside a band that ranges
from 0 up to a pre–defined threshold called α. The α value guarantees the co–
expression among genes. We have tested our method on the Yeast dataset and
compared the results to the biclustering algorithms of Cheng & Church (2000)
and Aguilar & Divina (2005). Results show that the algorithm finds interesting
biclusters, grouping genes with similar behaviors and maintaining a very low
mean squared residue.
Additional details
Identifiers
- URL
- https://idus.us.es/handle//11441/135689
- URN
- urn:oai:idus.us.es:11441/135689