Published 2018
| Version v1
Publication
Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score
- Creators
- Carbone, Marco
- Nardi, Alessandra
- Flack, Steve
- Carpino, Guido
- Varvaropoulou, Nikoletta
- Gavrila, Caius
- Spicer, Ann
- Badrock, Jonathan
- Bernuzzi, Francesca
- Cardinale, Vincenzo
- Ainsworth, Holly F
- Heneghan, Michael A
- Thorburn, Douglas
- Bathgate, Andrew
- Jones, Rebecca
- Neuberger, James M
- Battezzati, Pier Maria
- Zuin, Massimo
- Taylor-Robinson, Simon
- Donato, Maria F
- Kirby, John
- Mitchell-Thain, Robert
- Floreani, Annarosa
- Sampaziotis, Fotios
- Muratori, Luigi
- Alvaro, Domenico
- Marzioni, Marco
- Miele, Luca
- Marra, Fabio
- Giannini, Edoardo
- Gaudio, Eugenio
- Ronca, Vincenzo
- Bonato, Giulia
- Cristoferi, Laura
- Malinverno, Federica
- Gerussi, Alessio
- Stocken, Deborah D
- Cordell, Heather J
- Hirschfield, Gideon M
- Alexander, Graeme J
- Sandford, Richard N
- Jones, David E
- Invernizzi, Pietro
- Mells, George F
- Others:
- Carbone, Marco
- Nardi, Alessandra
- Flack, Steve
- Carpino, Guido
- Varvaropoulou, Nikoletta
- Gavrila, Caiu
- Spicer, Ann
- Badrock, Jonathan
- Bernuzzi, Francesca
- Cardinale, Vincenzo
- Ainsworth, Holly F
- Heneghan, Michael A
- Thorburn, Dougla
- Bathgate, Andrew
- Jones, Rebecca
- Neuberger, James M
- Battezzati, Pier Maria
- Zuin, Massimo
- Taylor-Robinson, Simon
- Donato, Maria F
- Kirby, John
- Mitchell-Thain, Robert
- Floreani, Annarosa
- Sampaziotis, Fotio
- Muratori, Luigi
- Alvaro, Domenico
- Marzioni, Marco
- Miele, Luca
- Marra, Fabio
- Giannini, Edoardo
- Gaudio, Eugenio
- Ronca, Vincenzo
- Bonato, Giulia
- Cristoferi, Laura
- Malinverno, Federica
- Gerussi, Alessio
- Stocken, Deborah D
- Cordell, Heather J
- Hirschfield, Gideon M
- Alexander, Graeme J
- Sandford, Richard N
- Jones, David E
- Invernizzi, Pietro
- Mells, George F
Description
Treatment guidelines recommend a stepwise approach to primary biliary cholangitis: all patients begin treatment with ursodeoxycholic acid (UDCA) monotherapy and those with an inadequate biochemical response after 12 months are subsequently considered for second-line therapies. However, as a result, patients at the highest risk can wait the longest for effective treatment. We determined whether UDCA response can be accurately predicted using pretreatment clinical parameters.
Additional details
- URL
- http://hdl.handle.net/11567/913298
- URN
- urn:oai:iris.unige.it:11567/913298
- Origin repository
- UNIGE