Published 2010 | Version v1
Publication

Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: from docking false positives to ATP-noncompetitive inhibitors.

Description

This work is focused on the hit optimization of previously identified dual Src/Abl inhibitors based on 1,3,4-thiadiazole and thiazole scaffolds.

Additional details

Created:
May 11, 2023
Modified:
November 22, 2023