Published February 12, 2018
| Version v1
Publication
Antimalarial activity of cupredoxins: the interaction of Plasmodium Merozoite Surface Protein 119 (MSP119) and Rusticyanin
Description
Background: The interaction of MSP119 with the cupredoxin azurin inhibits the growth of Plasmodium falciparum in red blood cells. Results: Rusticyanin forms a well-defined complex with MSP119 upon binding at the same surface area than inhibitory antibodies. Conclusion: Rusticyanin becomes an excellent therapeutic agent for malaria. Significance: Knowing the rusticyanin- MSP119 interface will allow the design of novel anti-malarial drugs
Abstract
Junta de Andalucía P08-CVI-3876, BIO198
Abstract
Ministerio de Economía y Competitividad SAF2011- 26611
Abstract
Fundación Séneca de la Región de Murcia 15354/PI/10
Abstract
Ministerio de Ciencia e Innovación BFU2010-19451
Abstract
Medical Research Council U117574558, U117532067
Additional details
- URL
- https://idus.us.es/handle//11441/70218
- URN
- urn:oai:idus.us.es:11441/70218
- Origin repository
- USE