Serum osteopontin levels are upregulated and predict disability after an ischaemic stroke

Creators: CARBONE, FEDERICO; Vuilleumier, Nicolas; Burger, Fabienne; Roversi, Gloria; Tamborino, Carmine; Casetta, Ilaria; Seraceni, Silva; Trentini, Alessandro; Padroni, Marina; DALLEGRI, FRANCO; Mach, François; Fainardi, Enrico; MONTECUCCO, FABRIZIO

Others:: Carbone, Federico; Vuilleumier, Nicola; Burger, Fabienne; Roversi, Gloria; Tamborino, Carmine; Casetta, Ilaria; Seraceni, Silva; Trentini, Alessandro; Padroni, Marina; Dallegri, Franco; Mach, Françoi; Fainardi, Enrico; Montecucco, Fabrizio

Description

After an acute ischaemic stroke (AIS), several inflammatory biomarkers have been investigated, but their predictive role on functional recovery remains to be validated. Here, we investigated the prognostic relevance of biomarkers related to atherosclerotic plaque calcification, such as osteopontin (OPN), osteoprotegerin (OPG) and the receptor activator of nuclear factor kappa-B ligand (RANKL) in a cohort of patients with AIS (n = 90) during 90-day follow-up.

Serum osteopontin levels are upregulated and predict disability after an ischaemic stroke

Description

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