LPdCl2(amine) Complexes Supported by Terphenyl Phosphanes: Applications in Aryl Amination Reactions

Description

Despite the excellent catalytic properties display by NHC-Pd-PEPPSI complexes in cross-coupling, phosphane analogs have been barely screened. In this work, we report the synthesis and characterization of a series of LPdCl2(amine) complexes bearing dialkylterphenyl phosphanes (PR2Ar′) and pyridine or morpholine ligands. The novel compounds have been tested as precatalysts in aryl amination reactions. The complex [(PCyp2ArXyl2)PdCl2(morpholine)] shows the best catalytic activity allowing the room-temperature coupling of aryl bromides and chlorides with aniline.

Abstract

Ministerio de Ciencia e Innovación PID2020-113797R

Abstract

Junta de Andalucía P20_00624

Abstract

European Commission (EC). Fondo Europeo de Desarrollo Regional US-1262266

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