The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study
- Creators
- Donati S.
- Corsi E.
- Maraschini A.
- Salvatore M. A.
- Baltaro F.
- Boldrini R.
- Bonassisa S.
- Brunelli R.
- Cagnacci A.
- Casucci P.
- Cataneo I.
- Cetin I.
- de Ambrosi E.
- Manso M. D.
- Fabiani M.
- Fieni S.
- Franchi M. P.
- Iurlaro E.
- Leo L.
- Liberati M.
- Sacchi L. L.
- Livio S.
- Locci M.
- Marozio L.
- Martini C.
- Maso G.
- Mecacci F.
- Meloni A.
- Mignuoli A. D.
- Moresi S.
- Patane L.
- Perotti F.
- Perrone E.
- Prefumo F.
- Ramenghi L.
- Rusciani R.
- Savasi V.
- Schettini S. C. A.
- Simeone D.
- Soligo M.
- Steinkasserer M.
- Tateo S.
- Ternelli G.
- Tironi R.
- Trojano V.
- Vergani P.
- Others:
- Donati, S.
- Corsi, E.
- Maraschini, A.
- Salvatore, M. A.
- Baltaro, F.
- Boldrini, R.
- Bonassisa, S.
- Brunelli, R.
- Cagnacci, A.
- Casucci, P.
- Cataneo, I.
- Cetin, I.
- de Ambrosi, E.
- Manso, M. D.
- Fabiani, M.
- Fieni, S.
- Franchi, M. P.
- Iurlaro, E.
- Leo, L.
- Liberati, M.
- Sacchi, L. L.
- Livio, S.
- Locci, M.
- Marozio, L.
- Martini, C.
- Maso, G.
- Mecacci, F.
- Meloni, A.
- Mignuoli, A. D.
- Moresi, S.
- Patane, L.
- Perotti, F.
- Perrone, E.
- Prefumo, F.
- Ramenghi, L.
- Rusciani, R.
- Savasi, V.
- Schettini, S. C. A.
- Simeone, D.
- Soligo, M.
- Steinkasserer, M.
- Tateo, S.
- Ternelli, G.
- Tironi, R.
- Trojano, V.
- Vergani, P.
Description
Introduction. This study aimed to estimate the incidence of SARS-CoV-2 infection among pregnant women during the first pandemic wave in Italy, and to describe CO-VID-19 disease characteristics and maternal and perinatal outcomes. Materials and methods. National population-based prospective cohort study collecting information on women with SARS-CoV-2 diagnosis, confirmed within 7 days from hospital admission. Results. The national SARS-CoV-2 rate was 6.04 per 1,000 births (95% CI 5.62-6.49) among pregnant women and 7.54 (95% CI 7.47-7.61) among women in reproductive age. 72.1% of the cohort developed mild COVID-19 disease without pneumonia nor need for ventilatory support. Severe disease was significantly associated with women's previous comorbidities (OR 2.55; 95% CI 0.98-6.90), obesity (OR 4.76; 95% CI 1.79-12.66) and citizenship from High Migration Pressure Countries (OR 3.43; 95% CI 1.27-9.25). Conclusions. During the first pandemic wave in Italy, the SARS-CoV-2 rate among pregnant women was lower compared to that detected among women of reproductive age, and risks of severe COVID-19 disease and adverse maternal and perinatal outcomes were rare.
Additional details
- URL
- http://hdl.handle.net/11567/1083071
- URN
- urn:oai:iris.unige.it:11567/1083071
- Origin repository
- UNIGE