Biocidal Cationic Macromolecules Irrespective of Bacterial Resistance: Our Best Achievements (Our Ongoing Studies)

Difficult-to-treat bacterial infections involving resistant human and plant pathogens, severely afflict hospitals and concern the agri-food sector. Bacteria of the genus Pseudomonas can quickly become resistant to antibiotics and spread such resistance to other bacteria. Species such as P. aeruginosa, P. putida and P. fluorescens, which normally produce antibiotics or help reduce some forms of pollution, can trigger serious nosocomial infections in humans. P. fragi is a major cause of dairy and meat spoilage, while P. syringae can infect a wide range of economically important plant species, including tobacco, kiwi and tomato. Therefore, new strategies and antibacterial agents capable of stopping these bacteria, regardless of their resistance to antibiotics, are urgently needed to limit serious human infections, food waste, plantation extermination and economic losses.