Published 2016
| Version v1
Publication
Treatment with aromatase inhibitors and markers of cardiovascular disease
Description
Purpose: The cardiovascular effects of estrogen deprivation induced by aromatase inhibitors are unknown. We carried out a cross-sectional study to evaluate the effect of estrogen deprivation induced by aromatase inhibitors on markers of cardiovascular risk. Methods: We enrolled 410 postmenopausal women: 200 consecutive breast cancer patients treated with aromatase inhibitors for a median of 53 months (range 23–122) and 210 volunteer controls. Carotid intima-media thickness, presence of carotid stenosis, and presence of abdominal aortic aneurism were evaluated through an ultrasound examination. Results: Average carotid intima-media thickness was 0.97 ± 0.02 mm and 1.08 ± 0.02 mm for breast cancer group and control group, respectively (pÂ
Additional details
Identifiers
- URL
- http://hdl.handle.net/11567/892189
- URN
- urn:oai:iris.unige.it:11567/892189
Origin repository
- Origin repository
- UNIGE